Spectroscopy characterization, theoretical study and antioxidant activities of the flavonoids-Pb(II) complexes

摘要

Lead is a prevalent toxic, nonessential heavy metal that has been considered as a major threat for human health. The intention of this work is to study the complexation of flavonoids (apigenin, chrysin, kaempferol and quercetin) with Pb(II) as well as antioxidant activities. The spectroscopy (AAS, UV-Vis, FT-IR, HPLC-MS, H-1 NMR) and density functional theory (DFT) calculation were carried out to analyze complexation of flavonoids with Pb(II). In addition, antioxidant abilities of flavonoids were analyzed by FRAP and ABTS assays. The results of study indicate that complexation abilities of kaempferol and quercetin are stronger than apigenin and chrysin. Additionally, the main complexes are formed by reaction of flavonoids (except quercetin) with Pb(II) in a ratio of 2:1. It is indicated that kaempferol and quercetin have a promising prospect of becoming care ingredients for lead elimination. (C) 2020 Published by Elsevier B.V.