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机译:发现菠萝蛋白酶和外末端(BET)蛋白的小分子降解剂,具有皮摩尔细胞效力,能够实现肿瘤回归
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Pathology Pharmaceutical Sciences Medicinal Chemistry and Pharmacology University of Michigan Ann Arbor Michigan 48109 United States;
机译:发现菠萝蛋白酶和外末端(BET)蛋白的小分子降解剂,具有皮摩尔细胞效力,能够实现肿瘤回归
机译:发现QCA570作为靶向嵌合(Protac)靶向嵌合体(Protac)的靶向有效和有效的蛋白水溶性溴琼瘤和蛋白质(BET)蛋白质,其能够诱导完全和耐用的肿瘤回归
机译:新型小分子的发现诱导了溴琼瘤和外末端(BET)溴蛋白BRD4和BRD2的选择性降解了细胞效力
机译:大鼠乳腺肿瘤引起的衰老过程中前列腺素,循环腺嘌呤3',5'-单磷酸盐和核蛋白磷酸化的相互关系。
机译:发现一个溴结构域的小分子降解剂和末端(BET)蛋白具有皮摩尔细胞的潜能并且能够实现肿瘤消退
机译:发现QCA570作为靶向嵌合(Protac)靶向嵌合体(Protac)的靶向有效和有效的蛋白水溶性溴琼瘤和蛋白质(BET)蛋白质,其能够诱导完全和耐用的肿瘤回归