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首页> 外文期刊>World neurosurgery >Comparison of the Effects of Propofol and Sevoflurane Induced Burst Suppression on Cerebral Blood Flow and Oxygenation: A Prospective, Randomised, Double-Blinded Study
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Comparison of the Effects of Propofol and Sevoflurane Induced Burst Suppression on Cerebral Blood Flow and Oxygenation: A Prospective, Randomised, Double-Blinded Study

机译:异丙酚和七氟醚诱导脉冲抑制对脑血流和氧化的影响的比较:一种前瞻性,随机,双盲研究

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摘要

OBJECTIVE: Pharmacologically induced electroenceph alogram (EEG) silence increases tolerance of ischemic period by reducing cerebral metabolism. We hypothesized that sevoflurane, a cerebral vasodilator, will maintain cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) better than propofol, a cerebral vasoconstrictor, during EEG silence. To validate this, we compared the effect of sevoflurane and propofol on CBF and CMRO2 during surgical plane of anasthesia (SP) and burst suppression on EEG (BS).
机译:目的:药理学诱导的Zeroctionalph群集(EEG)沉默通过降低脑代谢来增加缺血期的耐受性。 我们假设七氟醚,脑血管扩张剂,脑血管血流(CBF)和氧(CMOO2)的脑代谢率优于脑电图,脑血管电脑在脑电图中优于脑电图。 为了验证这一点,我们将七氟烷和异丙酚对CBF和CMRO2的效果进行了比较了厌氧(SP)手术平面和EEG(BS)的突发抑制期间。

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