A novel popamine-imprinted chitosan/CuCo2O4@carbon/three-dimensional macroporous carbon integrated electrode

摘要

A novel Cu-Co-zeolite imidazole framework (Cu-Co-ZIF)-derived CuCo2O4@carbon nanocomposites supported on three-dimensional porous carbon (3D-KSC) were prepared to develop molecularly imprinted electrochemical sensors for sensing dopamine (DA). Firstly, polyhedral Cu-Co-ZIF was synthesized at room temperature and uniformly arrayed on 3D-KSC, and then the CuCo2O4@carbon nanostructure was obtained by high-temperature carbonization under nitrogen atmosphere. Finally, the molecularly imprinted polymer (MIPs) DA-imprinted chitosan was covered by potentiostatic electrodeposition to obtain the MIPs/CuCo2O4@carbon/3D-KSC integrated electrode. The results showed 15 umsized polyhedral Cu-Co-ZIF crystals were transformed into smaller irregular porous CuCo2O4@carbon nanocomposites with rough surface by calcination. Here, the produced 5 nm-sized CuCo2O4 crystals were uniformly embedded into the N-doped porous carbon frameworks. Various experimental conditions including the amount of Cu-Co-ZIF grew on 3D-KSC, calcination temperature, electrodepositing time of MIPs, the eluted time of template molecule and the pH of electrolyte were explored. The as-prepared MIPs/CuCo2O4@carbon/3D-KSC integrated electrode exhibited excellent anti-interference ability and good stability. The sensitivity for DA detection was 720.8 mu A mM(-1) cm(-2), the detection range was 0.51 mu M -1.95 mM, and the detection limit was 0.16 mu M. (C) 2019 Elsevier B.V. All rights reserved.