首页> 外文期刊>Transplantation: Official Journal of the Transplantation Society >Has the Department of Veterans Affairs Found a Way to Avoid Racial Disparities in the Evaluation Process for Kidney Transplantation?
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Has the Department of Veterans Affairs Found a Way to Avoid Racial Disparities in the Evaluation Process for Kidney Transplantation?

机译:退伍军人事务部是否找到了一种方法来避免肾移植评估过程中的种族差异?

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Background. Minority groups are affected by significant disparities in kidney transplantation (KT) in Veterans Affairs (VA) and non-VA transplant centers. However, prior VA studies have been limited to retrospective, secondary database analyses that focused on multiple stages of the KT process simultaneously. Our goal was to determine whether disparities during the evaluation period for KT exist in the VA as has been found in non-VA settings. Methods. We conducted a multicenter longitudinal cohort study of 602 patients undergoing initial evaluation for KT at 4 National VA KT Centers. Participants completed a telephone interview to determine whether, after controlling for medical factors, differences in time to acceptance for transplant were explained by patients' demographic, cultural, psychosocial, or transplant knowledge factors. Results. There were no significant racial disparities in the time to acceptance for KT [Log-Rank chi(2) = 1.04; P = 0.594]. Younger age (hazards ratio [HR], 0.98; 95% confidence interval [CI], 0.97-0.99), fewer comorbidities (HR, 0.89; 95% CI, 0.84-0.95), being married (HR, 0.81; 95% CI, 0.66-0.99), having private and public insurance (HR, 1.29; 95% CI, 1.03-1.51), and moderate or greater levels of depression (HR, 1.87; 95% CI, 1.03-3.29) predicted a shorter time to acceptance. The influence of preference for type of KT (deceased or living donor) and transplant center location on days to acceptance varied over time. Conclusions. Our results indicate that the VA National Transplant System did not exhibit the racial disparities in evaluation for KT as have been found in non-VA transplant centers.
机译:背景。少数群体受退伍军人事务(VA)和非VA移植中心的肾移植(KT)的显着差异的影响。然而,先前的VA研究仅限于回顾性的次要数据库分析,其同时聚焦KT过程的多个阶段。我们的目标是确定在VA中存在的VA中KT评估期间的差异是否存在于非VA设置中。方法。我们在4名国家VA KT中心进行了602名患者初步评估的多中心纵向队列研究。与会者完成了电话采访,以确定在控制体内因素后,患者人口统计,文化,心理社会或移植知识因素解释了对移植的差异。结果。在接受KT [Log-Rank Chi(2)= 1.04时没有显着的种族差异; p = 0.594]。较年轻的年龄(危险比[HR],0.98; 95%置信区间[CI],0.97-0.99),较少的合并症(HR,0.89; 95%CI,0.84-0.95),已婚(HR,0.81; 95%CI ,0.66-0.99),拥有私人和公共保险(HR,1.29; 95%CI,1.03-1.51)和中度或更高水平的抑郁症(HR,1.87; 95%CI,1.03-3.29)预测了更短的时间验收。偏爱Kt(死者或活体供体)和移植中心位置的影响在几天内接受随时间变化。结论。我们的结果表明,VA国家移植系统未在非VA移植中心中发现的KT评估中的种族差异。

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