Liver Transplantation With Old Grafts: A Ten-Year Experience

摘要

Abstract Background The persistent scarcity of donors has prompted liver transplantation teams to find solutions for increasing graft availability. We report our experience of liver transplantations performed with grafts from older donors, specifically over 70 and 80 years old. Patients and methods We analyzed our prospectively maintained single-center database from January 1, 2005, to December 31, 2014, with 380 liver transplantations performed in 354 patients. Six groups were composed according to donor age:?Results Donors?80 years of age. Patient survival was not significantly different between the groups. In multivariate analysis, factors predicting graft loss were transaminase peak, retransplantation and cold ischemia time but not donor age. Conclusions Older donors >70 and >80 years of age could provide excellent liver grafts. Highlights " We analyzed 380 liver transplantations performed between 2005 and?015. " Of the donors, 16.8% were >70 years of age and 7% were >80 years of age. " Results of liver transplantations with grafts from carefully selected older donors were excellent.