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Improvement in nasal obstruction and quality of life after septorhinoplasty and turbinate surgery

机译:静脉内成形术后鼻梗阻和鼻腔膜手术后的鼻梗阻和生活质量

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Objectives To evaluate the long‐term impact of functional septorhinoplasty (SRP) with and without inferior turbinate reduction (ITR) on disease‐specific symptom severity and general health‐related quality of life (QOL). Study Design Prospective cohort study at a tertiary referral center. Methods Patients undergoing functional SRP with and without ITR were administered the Nasal Obstruction Symptom Evaluation (NOSE) scale to assess severity of nasal obstruction and the EuroQol‐5 Dimension Questionnaire Visual Analog Scale (EQ‐5D VAS) to assess general health‐related QOL preoperatively and at 2, 4, 6, 12, 24, and 36?months postoperatively. Patient demographics, surgical technique, symptom severity, and QOL outcomes were analyzed. Results A total of 567 patients were included, with 391 patients undergoing functional SRP alone (54.0% female; mean age 36.0?years [standard deviation (SD):16.2]) and 176 patients undergoing functional SRP with ITR (50.0% female; mean age 35.6?years [SD:13.6]). There was a significant decrease in NOSE and increase in EQ‐5D VAS scores in both groups through at least 24?months postoperatively. Change in NOSE scores was negatively correlated with change in EQ‐5D VAS ( r =??0.38, P ?0.01). Compared to patients undergoing SRP, patients also undergoing ITR had a statistically but nonclinically significant improvement in NOSE, with similar trends for EQ‐5D VAS that were not significant. Conclusion SRP results in a sustained, long‐term improvement in nasal obstruction based on disease‐specific and general health‐related QOL measures, with incremental improvement in outcomes with addition of ITR. This study provides the foundation for defining health outcomes and the health utility value of surgical interventions that address nasal obstruction. Level of Evidence 2c Laryngoscope , 129:1554–1560, 2019
机译:目的是评估功能性静脉内成形术(SRP)的长期影响(SRP)与疾病特异性症状严重程度和一般健康相关生活质量(QOL)的疾病特异性症状减少(ITR)。第三次推荐中心研究设计预期队列研究。方法介绍鼻塞症状评估(鼻子)展示鼻塞症状评估(鼻子)术后患有鼻塞症状评估(鼻子)的患者,以评估鼻塞的严重程度和欧元QOL-5尺寸问卷调查问卷(EQ-5D VAS),以术前评估一般健康相关的QOL在术后2,4,6,12,24和36个月。分析了患者人口统计,手术技术,症状严重程度和QOL结果。结果共用了567名患者,单独进行391名患者进行功能性SRP(54.0%的女性;平均年龄36.0?岁月[标准差(SD):16.2])和176名患有ITR功能SRP的患者(50.0%的女性;意味着35.6岁?年[SD:13.6])。在术后至少24个月内,两组中,两组的EQ-5D VAS分数有显着降低。鼻子分数的变化与EQ-5D VAS的变化负相关(r = = 0.38,p&?0.01)。与接受SRP的患者相比,患者也在鼻窦上进行统计而非截然不同的改善,具有不显着的EQ-5D VAS的类似趋势。结论SRP基于疾病特异性和一般健康相关的QOL措施导致鼻塞持续,长期改善,随着ITR的增加而逐步改善。本研究为定义了健康结果以及解决鼻阻塞的外科干预的健康效用价值的基础。证据水平2C喉镜,129:1554-1560,2019

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