We read with a great surprise that Sarah Walters and colleagues presented their Case Report (June 28, p 2268) as an atypical case of Whipple's disease. 50% of the patients with Whipple's disease have lymphadenopathies at the time of diagnosis, mainly mediastinal and mesenteric, and they are a typical presentation of the disease.Knowledge of Whipple's disease and Tropheryma whipplei infections has increased greatly in the past few years. We were surprised that the authors had not used more recent references than one from 2007.19% of all papers published on Whipple's disease were published in the past 7 years, and of the reports referenced in ISI Web Of Knowledge about Whipple's disease or T whipplei, nearly 50% have been published since 2007.
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