Buccoadhesive Dosage Form Containing Antifungal Agent for Treating Oropharyngeal Candidiasis:A Review One More Buccoadhesive Antifungal for Oropharyngeal Candidiasis

摘要

Dear Editor,In the above mentioned review article, a comprehensive list of active ingredients investigated in bioadhesive dosage forms for the treatment of OPC was presented, various kind of active agents and dosage forms have been mentioned but one agent Miconazole base is omitted. The active ingredients are Miconazole 50 mg buccal tablet (MBT) (Oravig?, Strativa Pharmaceuticals). Miconazole nitrate 10 mg buccal tablets (Tibozole?, Tibotec Pharmaceuticals) The above mentioned buccal tablets were used in the treatment for OPC. However, the two miconazole buccal tablets are distinct products, and each contains different polymers. MBT utilizes a hydrophilic matrix containing the polymer hypermellose, which allows immediate and sustained release of Miconazole [1].