Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations

Murray Gerald L.; Bodiyabadu Kaveesha; Danielewski Jennifer; Garland Suzanne M.; Machalek Dorothy A.; Fairley Christopher K.; Jensen Jorgen S.; Williamson Deborah A.; Tan Lit Y.; Mokany Elisa; Durukan Duygu; Bradshaw Catriona S.

首页> 外文期刊>The Journal of Infectious Diseases >Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations

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Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations

机译：Moxifloxacin和Sitafloxacin治疗衰竭在支原体中感染：与Parc突变结合G248T（S83i）和同时的陀螺突变

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Background. The basis of fluoroquinolone treatment failure for Mycoplasma genitalium is poorly understood.

机译：背景。氟代喹啉治疗衰竭的基础术治药物基因生长率较差。

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来源
《The Journal of Infectious Diseases》 |2020年第6期|共8页
作者
Murray Gerald L.; Bodiyabadu Kaveesha; Danielewski Jennifer; Garland Suzanne M.; Machalek Dorothy A.; Fairley Christopher K.; Jensen Jorgen S.; Williamson Deborah A.; Tan Lit Y.; Mokany Elisa; Durukan Duygu; Bradshaw Catriona S.;
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作者单位

Univ Melbourne Dept Obstet &

Gynaecol Parkville Vic Australia;

Royal Womens Hosp Ctr Womens Infect Dis Parkville Vic Australia;

Royal Womens Hosp Ctr Womens Infect Dis Parkville Vic Australia;

Univ Melbourne Dept Obstet &

Gynaecol Parkville Vic Australia;

Royal Womens Hosp Ctr Womens Infect Dis Parkville Vic Australia;

Alfred Hlth Melbourne Sexual Hlth Ctr Carlton Vic Australia;

Statens Serum Inst Copenhagen Denmark;

Univ Melbourne Peter Doherty Inst Infect &

Immun Microbiol Diagnost Unit Publ Hlth Lab;

SpeeDx Sydney NSW Australia;

SpeeDx Sydney NSW Australia;

Alfred Hlth Melbourne Sexual Hlth Ctr Carlton Vic Australia;

Alfred Hlth Melbourne Sexual Hlth Ctr Carlton Vic Australia;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Mycoplasma genitalium; fluoroquinolone; antibiotic resistance; treatment failure; mutation;

机译：支原体霉菌素;氟喹诺酮;抗生素抗性;治疗失败;突变;

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专利

1. Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations [J] . Murray Gerald L., Bodiyabadu Kaveesha, Danielewski Jennifer, The Journal of Infectious Diseases . 2020,第6期

机译：Moxifloxacin和Sitafloxacin治疗衰竭在支原体中感染：与Parc突变结合G248T（S83i）和同时的陀螺突变
2. Lack of Association Between the S83I ParC Mutation in Mycoplasma genitalium and Treatment Outcomes Among Men Who Have Sex With Men with Nongonococcal Urethritis [J] . Chambers Laura C., Jensen Jorgen S., Morgan Jennifer L., Sexually transmitted diseases . 2019,第12期

机译：S83i Parc突变缺乏关联的支原体生长率和治疗结果与患有非农心尿道炎发生性关系的男性
3. Mycoplasma genitalium infection: current treatment options, therapeutic failure, and resistance-associated mutations [J] . Deborah L Couldwell, David A Lewis Infection and Drug Resistance . 2015,第3期

机译：生殖道支原体感染：当前的治疗选择，治疗失败和耐药相关突变
4. A concurrent commutation failure detection method for multi-infeed HVDC systems [C] . Xiyang Liu, Zengping Wang, Yujin Yang, IEEE Workshop on control and modeling for power electronics . 2017

机译：多馈HVDC系统并发换相故障检测方法
5. Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains [O] . Ryoichi Hamasuna, Phuong Thi Le, Satoshi Kutsuna, 2012

机译：莫西沙星耐药和易感支原体生殖器菌株的ParC和GyrA突变
6. O04.4 Mycoplasma genitalium parC and gyrAmutations associated with moxifloxacin and sitafloxacin treatment failure [O] . Gerald Murray, Catriona Bradshaw, Kaveesha Bodiyabadu, 2019

机译：o04.4支原体Gencalium parc和与moxifloxacin相关的Gyramutation和Sitafloxacin治疗失败

Moxifloxacin and Sitafloxacin Treatment Failure in Mycoplasma genitalium Infection: Association with parC Mutation G248T (S83I) and Concurrent gyrA Mutations

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