Remobilizing P elements out of the stambh A locus of Drosophilamelanogaster

摘要

P elements from two P-tagged alleles, stm A(P1) and stm A(P4), of the temperature-sensitive paralytic mutant stambh A (stm A) were remobilized to derive wild-type revertants and P excision lethals. stm Apt remutated to lethality, while stm A(P4) reverted to the wild type. The P excision lethals are not amorphic mutations, since they were weaker in paralytic phenotype (i) than the parental P-tagged allele and (ii) for deficiencies for stm A. The lethals collectively affected all stages of the life cycle, demonstrating that stm A(+) is needed throughout fly development.