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首页> 外文期刊>Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry >Development of a water-soluble 3-formylBODIPY dye for fluorogenic sensing and cell imaging of sulfur dioxide derivatives
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Development of a water-soluble 3-formylBODIPY dye for fluorogenic sensing and cell imaging of sulfur dioxide derivatives

机译:一种用于水溶性3-甲甲基小径染料的氟二氧化硫衍生物的荧光传感和细胞成像

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摘要

A new water-soluble, highly fluorogenic 3-formylBODIPY dye that enables the sensing of SO2 derivatives in aqueous buffers and cancer cells is reported. The quaternary ammonium group appended through the mesa-position of the BODIPY dye ensures water solubility. The probe exhibits high specificity for cytosolic (bi)sulfites and fluoresces brightly in human lung adenocarcinoma cells (A549). (C) 2019 Elsevier Ltd. All rights reserved.
机译:据报道,一种新的水溶性高度荧光的3-甲酰基二十甲基染料,其能够在水性缓冲液和癌细胞中感测SO2衍生物。 亚赤浮染料的MESA位置附加的季铵基团确保水溶解度。 探针对人肺腺癌细胞中的细胞溶胶(BI)硫酸盐和荧光显着,探针具有高特异性(A549)。 (c)2019 Elsevier Ltd.保留所有权利。

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