Efficient and selective palladium-catalyzed direct oxidative esterification of benzylic alcohols under aerobic conditions

摘要

AbstractA highly efficient palladium-catalyzed approach for the direct oxidative esterification of benzylic alcohols with methanol and long-chain aliphatic alcohols under mild conditions has been achieved. This practical catalyst system exhibits a broad substrate scope and good functional group tolerance. Catalytic amount of Bi(OTf)3is used as co-catalyst to improve the activity and selectivity of the reactions. A variety of esters are obtained in yields of 43–96%.Graphical abstractDisplay Omitted]]>