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首页> 外文期刊>Nature reviews Cancer >Clinical Manifestation of Acute, Subacute, and Chronic Low Back Pain in Different Age Groups: Low Back Pain in 35,446 Patients
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Clinical Manifestation of Acute, Subacute, and Chronic Low Back Pain in Different Age Groups: Low Back Pain in 35,446 Patients

机译:急性,亚急性和慢性低腰疼痛在不同年龄组中的临床表现:35,446名患者的腰痛

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Background Low back pain (LBP) is a major healthcare problem causing tremendous economic costs. Methods Results Clinical manifestation of LBP was characterized in 35,446 patients. We focused on the comparison of the acute, subacute, and chronic LBP stage with regard to patients' ages, based on epidemiologic and clinical questionnaires (eg, painDETECT Questionnaire, Pain Disability Index), pain intensity, pain descriptors, and functional impairment. We found that neuropathic components were most frequent in chronic LBP patients at the ages of 51 to 60 years. Elderly LBP patients showed a decrease in neuropathic and an increase in nociceptive pain. The most frequently reported pain descriptors were "pressure pain" and "pain attacks" through all stages of LBP, whereas "burning" and "prickling" were most frequent in the chronic stage. Patients after back surgery presented neuropathic pain symptoms most frequently and had the highest amount of pain medication intake. Conclusions Burning and prickling were revealed as possible indicators for LBP chronicity. Combined with pain attacks and pressure pain, these 4 pain descriptors might be a promising adjunct to pain intensity in terms of outcome parameters for future LBP studies. The decrease of neuropathic pain syndromes in the elderly might be explained by degenerative processes. The presented work provides important insights on LBP management in the acute, subacute, and chronic stages.
机译:背景技术腰痛(LBP)是一个主要的医疗问题,导致巨大的经济成本。方法结果,LBP的临床表现特征在35,446名患者中。基于流行病学和临床问卷(例如,止痛调查问卷,止痛性指数),疼痛强度,疼痛描述符和功能性损害,我们专注于患者年龄的急性,亚急性和慢性LBP阶段的比较。我们发现神经病成分在慢性LBP患者中最常见的51至60岁。老年LBP患者显示出神经疗法的降低和伤害性疼痛的增加。通过LBP的所有阶段,最常见的疼痛描述符是“压力疼痛”和“疼痛攻击”,而“燃烧”和“刺耳”在慢性阶段最常常见。背部手术后的患者最常呈现神经性疼痛症状,并且具有最多的止痛药物摄入量。结论燃烧和刺痛被揭示了LBP慢性的可能指标。结合疼痛攻击和压力疼痛,这4个疼痛描述符可能是未来LBP研究的结果参数方面有前途的疼痛强度。可通过退行过程解释老年人神经病疼痛综合征的降低。本工作在急性,亚急性和慢性阶段的LBP管理方面提供了重要的见解。

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