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Geometric distortion characterization and correction for the 1.0?T Australian MRI‐linac system using an inverse electromagnetic method

机译:使用反向电磁法的1.0?T澳大利亚MRI-LINAC系统的几何失真特征和校正

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摘要

Purpose The magnetic resonance imaging (MRI)‐Linac system combines a MRI scanner and a linear accelerator (Linac) to realize real‐time localization and adaptive radiotherapy for tumors. Given that the Australian MRI‐Linac system has a 30‐cm diameter of spherical volume (DSV) with a shimmed homogeneity of ±4.05 parts per million (ppm), a gradient nonlinearity (GNL) of 5% can only be assured within 15?cm from the system's isocenter. GNL increases from the isocenter and escalates close to and outside of the edge of the DSV. Gradient nonlinearity can cause large geometric distortions, which may provide inaccurate tumor localization and potentially degrade the radiotherapy treatment. In this study, we aimed to characterize and correct the geometric distortions both inside and outside of the DSV. Methods On the basis of phantom measurements, an inverse electromagnetic (EM) method was developed to reconstitute the virtual current density distribution that could generate gradient fields. The obtained virtual EM source was capable of characterizing the GNL field both inside and outside of the DSV. With the use of this GNL field information, our recently developed “GNL‐encoding” reconstruction method was applied to correct the distortions implemented in the k ‐space domain. Results Both phantom and in vivo human images were used to validate the proposed method. The results showed that the maximal displacements within an imaging volume of 30?cm?×?30?cm?×?30?cm after using the fifth‐order spherical harmonic (SH) method and the proposed method were 6.1?±?0.6?mm and 1.8?±?0.6?mm, respectively. Compared with the fifth‐order SH‐based method, the new solution decreased the percentage of markers (within an imaging volume of 30?cm?×?30?cm?×?30?cm) with ≥1.5‐mm distortions from 6.3% to 1.3%, indicating substantially improved geometric accuracy. Conclusions The experimental results indicated that the proposed method could provide substantially improved geometric accuracy for the region outside of the DSV, when comparing with the fifth‐order SH‐based method.
机译:目的,磁共振成像(MRI)-Linac系统结合了MRI扫描仪和线性加速器(LINAC)来实现肿瘤的实时定位和自适应放疗。鉴于澳大利亚MRI-LINAC系统具有30厘米的球形体积(DSV)直径,均匀均匀性为±4.05份(PPM),梯度非线性(GNL)的级别仅在来自系统的Isocenter 15?cm。 GNL从Isocenter增加,靠近和DSV边缘的升级。梯度非线性可能导致大的几何失真,其可以提供不准确的肿瘤定位并可能降解放射治疗。在这项研究中,我们旨在表征和校正DSV内外的几何扭曲。方法基于幻像测量,开发了逆电磁(EM)方法以重建可能产生梯度字段的虚拟电流密度分布。所获得的虚拟EM源能够在DSV内部和外部表征GNL字段。通过使用此GNL现场信息,我们最近开发的“GNL编码”重建方法被应用于校正K -Space域中实现的失真。结果幻象和体内人类图像都用于验证所提出的方法。结果表明,在使用第五阶球面谐波(SH)方法的成像体积内的成像体积内的最大位移在30Ω·×30Ω·厘米?×30℃,所提出的方法是6.1?±0.6? mm和1.8?±0.6?mm。与基于第五阶SH的方法相比,新溶液降低了标记的百分比(在30Ω·×30Ω·30Ω·30Ω·30Ω·30Ω·30Ω·×30?×30?cm的成像体积内,≥1.5毫米的畸变为6.3%为1.3%,表明几何精度显着提高。结论的实验结果表明,所提出的方法可以提供显着改善的用于DSV的区域之外的几何精度,与五阶基于SH-方法比较时。

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