Integration of Flow Chemistry in Multistep Syntheses

摘要

Flow chemistry has become an important tool for synthetic chemists, not only in the academic, heavily research-based environment but also for industrial chemists, who are often faced with the challenge of producing compounds in large quantities. Demands and restrictions such as cost, purity, safety, and accessibility of reagents and starting materials might vary in these two different environments, but flow synthesis allows many of these issues to be addressed. I am very happy that many researchers at the forefront of flow chemistry in academia as well as in industry have contributed to this special issue on multistep flow synthesis. The Integration of Flow Chemistry in Multistep Syntheses is taking standalone flow protocols to the next level by utilizing them either in consecutive flow processes or as part of sequences with batch protocols. Either combination allows taking the highest advantage of flow processes in synthesis and even permits new synthetic strategies to be pursued.