Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2 (vol 158, pg 814, 2018)

Shi Wei; Qiang Hao; Huang Dandan; Bi Xinzhou; Huang Wenlong; Qian Hai

首页> 外文期刊>European Journal of Medicinal Chemistry: Chimie Therapeutique >Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2 (vol 158, pg 814, 2018)

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Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2 (vol 158, pg 814, 2018)

机译：新型Pyrrolo探索[2,1-F] [1,2,4]三嗪衍生物具有改善的抗癌疗效，作为C-Met / Vegfr-2的双重抑制剂（Vol 158，PG 814,2018）

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来源
《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2020年第2020期|共1页
作者
Shi Wei; Qiang Hao; Huang Dandan; Bi Xinzhou; Huang Wenlong; Qian Hai;
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China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

China Pharmaceut Univ Ctr Drug Discovery State Key Lab Nat Med 24 Tongjiaxiang Nanjing 210009;

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正文语种 eng
中图分类药学;
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1. Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2 (vol 158, pg 814, 2018) [J] . Shi Wei, Qiang Hao, Huang Dandan, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2020,第期

机译：新型Pyrrolo探索[2,1-F] [1,2,4]三嗪衍生物具有改善的抗癌疗效，作为C-Met / Vegfr-2的双重抑制剂（Vol 158，PG 814,2018）
2. Synthesis, SAR, and Evaluation of 4-(2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino)pyrrolo(2,1-f)(1,2,4)triazine -based VEGFR-2 kinase inhibitors. [J] . Cai ZW, Wei D, Borzilleri RM, Bioorganic and Medicinal Chemistry Letters . 2008,第4期

机译：基于4-（2,4-二氟-5-（环丙基氨基甲酰基）苯基氨基）吡咯并（2,1-f）（1,2,4）三嗪的VEGFR-2激酶抑制剂的合成，SAR和评价。
3. Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo(2,1-f)(1,2,4)triazine based VEGFR-2 kinase inhibitors. [J] . Borzilleri RM, Cai ZW, Ellis C, Bioorganic and Medicinal Chemistry Letters . 2005,第5期

机译：基于4-（3-羟苯基氨基）吡咯并（2,1-f）（1,2,4）三嗪的VEGFR-2激酶抑制剂的合成和SAR。
4. Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design synthesis anticancer activity and effect on cell cycle profile [O] . Aml E.-S. Mghwary, Ehab M. Gedawy, Aliaa M. Kamal, 2019

机译：新型的噻吩并嘧啶衍生物作为EGFR和VEGFR-2双重抑制剂：设计合成抗癌活性以及对细胞周期的影响

Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2 (vol 158, pg 814, 2018)

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