Synthesis, Characterization and Antibacterial Study of Copper Oxide-Graphene Nanocomposites

摘要

A novel facile synthesis of copper oxide and copper-graphene oxide nanocomposites were achieved by modified sol-gel technique for their pharmaceutical and therapeutic use. Spherical, crystalline, defect free CuO nanoparticles with average diameter 20 nm were synthesized by modified sol-gel technique. Reduced graphene oxide (rGO) was synthesized by modified Hummers method. Copper-graphene oxide nanocomposites (CuGONC) were synthesized by in situ method. The crystalline nature, size, shape and dimensions of the nanoparticles, graphene oxide and nanocomposites were studied by X-Ray diffraction method. TEM analysis was carried out to examine the morphology of nanoparticles and nanocomposites. FOR spectroscopy confirms that the CuO nanoparticles are surrounded by oxygen and silicon atoms. Antibacterial activity of CuO nanoparticles and CuGONC were investigated against gram positive and gram negative bacteria. Zone of Inhibition shown by CuO nanoparticles and CuGONC was found to be higher than six investigated standard antibiotics. Synthesized Copper oxide nanoparticles and nanocomposites can be used as antibacterial agents. This eco-friendly method of synthesis of CuO nanoparticles and CuGONC could be a viable solution for industrial applications and therapeutic needs.