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Follow-Up Care, Surveillance Protocol, and Secondary Prevention Measures for Survivors of Colorectal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement

机译:大肠癌幸存者的随访护理,监测方案和二级预防措施:美国临床肿瘤学会临床实践指南认可

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Purpose The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for endorsing recent clinical practice guidelines that have been developed by other professional organizations. Methods The Cancer Care Ontario (CCO) Guideline on Follow-up Care, Surveillance Protocol, and Secondary Prevention Measures for Survivors of Colorectal Cancer was reviewed by ASCO for methodologic rigor and considered for endorsement. Results The ASCO Panel concurred with the CCO recommendations and recommended endorsement, with the addition of several qualifying statements. Conclusion Surveillance should be guided by presumed risk of recurrence and functional status of the patient (important within the first 2 to 4 years). Medical history, physical examination, and carcinoembry-onic antigen testing should be performed every 3 to 6 months for 5 years. Patients at higher risk of recurrence should be considered for testing in the more frequent end of the range. A computed tomography scan (abdominal and chest) is recommended annually for 3 years, in most cases. Positron emission tomography scans should not be used for surveillance outside of a clinical trial. A surveillance colonoscopy should be performed 1 year after the initial surgery and then every 5 years, dictated by the findings of the previous one. If a colonoscopy was not preformed before diagnosis, it should be done after completion of adjuvant therapy (before 1 year). Secondary prevention (maintaining a healthy body weight and active lifestyle) is recommended. If a patient is not a candidate for surgery or systemic therapy because of severe comorbid conditions, surveillance tests should not be performed. A treatment plan from the specialist should have clear directions on appropriate follow-up by a nonspecialist.
机译:目的美国临床肿瘤学会(ASCO)制定了一项政策和一套程序,以认可由其他专业组织制定的最新临床实践指南。方法ASCO审查了安大略省大肠癌幸存者随访护理,监测方案和二级预防措施的指南,以确保其方法学严格性,并考虑予以认可。结果ASCO小组同意CCO的建议并推荐认可,并添加了一些合格声明。结论监测应以患者的复发风险和功能状态(在头2至4年内重要)为指导。应每3至6个月进行病史,体格检查和癌胚抗原检测,持续5年。复发风险较高的患者应考虑在更频繁的范围内进行检查。大多数情况下,建议每年进行一次计算机断层扫描(腹部和胸部),持续3年。正电子发射断层扫描不能用于临床试验之外的监视。初次手术后一年应进行结肠镜检查,然后每5年进行一次结肠镜检查,具体取决于前一次的发现。如果在诊断之前未进行结肠镜检查,则应在辅助治疗完成后(1年之前)进行。建议进行二级预防(保持健康的体重和积极的生活方式)。如果患者由于严重的合并症而不适合手术或全身治疗,则不应进行监视测试。专科医生的治疗计划应明确指示非专科医生应采取适当的后续措施。

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