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A Study of Antimicrobial Property of Textile Fabric Treated with Modified Dendrimers

机译:改性树枝状聚合物处理织物的抗菌性能研究

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摘要

Dendrimers have been used as a vehicle todevelop the antimicrobial properties of textile fabrics. Wehave taken advantage of the large number of functionalgroups present in the regular and highly branched three-dimensional architecture of dendrimers. In this study, thepoly(amidoamine) (PAMAM) G-3 dendrimer was modifiedto provide antimicrobial properties. Following a proceduresimilar to what is suggested in the literature, PAMAM (G3)with primary amine end groups was converted into ammo-nium functionalities. The modification was then confirmedby FTIR and ~(13)C-NMR analysis. Dendrimers have uniqueproperties owing to their globular shape and tunable cav-ities, this allows them to form complexes with a variety ofions and compounds; and also act as a template to fabricate metal nanoparticles. AgNO_3—PAMAM (G3) complex as wellas a MesoSilver—PAMAM (G3) complex were formed andthese modified dendrimers were characterized by a UV—Visible spectrophotometer to study the complex formation.Modified dendrimers were applied to the Cotton/Nylonblend fabric. SEM and EDX analysis were performed tostudy the dispersion of silver nanoparticles onto the fabric.An antimicrobial test of the treated-fabric against Staphylo-coccus aureus exhibited significant biocidal activities for eachtype of modified-dendrimer.
机译:树枝状聚合物已被用作开发纺织品抗微生物性能的媒介。我们已经利用了树枝状聚合物的规则和高度分支的三维结构中存在的大量官能团。在这项研究中,对聚(酰胺基胺)(PAMAM)G-3树状聚合物进行了改性,以提供抗菌性能。按照类似于文献中所建议的方法,将具有伯胺端基的PAMAM(G3)转化为铵官能团。然后通过FTIR和〜(13)C-NMR分析确认修饰。树枝状大分子由于其球形形状和可调节的空腔而具有独特的性能,这使它们可以与多种离子和化合物形成复合物。并且还充当制造金属纳米粒子的模板。形成了AgNO_3-PAMAM(G3)配合物以及MesoSilver-PAMAM(G3)配合物,并使用紫外可见分光光度计对这些改性的树枝状聚合物进行了表征,以研究该复合物的形成。进行了SEM和EDX分析以研究银纳米颗粒在织物上的分散性。处理过的织物对金黄色葡萄球菌的抗菌测试表明,每种类型的改性树状聚合物均具有显着的杀菌活性。

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