Synthesis and property of hydrogel membranes consisting of fumaramate with phosphorylcholine group

摘要

Fumaramate bearing a phosphoryl choline group, isopropyl-2-[2'-(trimethylammonium) ethyl phosphoryl] ethyl fumaramate (IPTPFA), was radically copolymerized with 2-hydroxyethylmethacrylate (HEMA) in the presence of various crosslinking agents, water, and 2,2'-azobis(isobutyronitrile) to obtain hydrogel membranes. The obtained hydrogel membranes adsorbed bovine serum albumin (BSA) much less than those of poly(HEMA), and the values of water content (H) were higher than those of poly(HEMA). The values of tensile strength and tensile elongation of the hydrogel were 68.4 g/mm(2) and 239%, respectively. (C) 2004 Wiley Periodicals, Inc. [References: 18]