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Physical therapy and hip osteoarthritis - Reply

机译:物理疗法和髋骨关节炎-回复

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In Reply Dr White and colleagues raise 4 issues. First, they are concerned about differential treatment effects according to disease severity given that half of our participants had moderate to severe hip osteoarthritis and that their experience shows that those with moderate to severe hip osteoarthritis do not respond as favorably to most conservative treatment. This is a possibility although an exploratory post hoc analysis of the data showed no significant differences in the amount of improvement in pain (P = .76) and function (P = .38) comparing disease severity subgroups with active and sham treatment.Second, White and colleagues question the dose and content of the active intervention. We evaluated a program that was designed to match common clinical practice parameters in Australia and internationally. Whether a more intensive program with a greater number of exercises and greater supervised contact time would be more effective remains to be tested. However, given that longer-term adherence is problematic, the feasibility of such a program needs to be considered in the context of a chronic disease such as osteoarthritis.Third, the authors speculate that the adverse events may have been sustained from hip thrust manipulation. We cannot ascertain the cause of the adverse events given the multimodal nature of the program. However, few adverse events were noted from this same technique in another trial of hip osteoarthritis.1
机译:作为回应,怀特博士及其同事提出了4个问题。首先,考虑到我们一半的参与者患有中度至重度髋骨关节炎,他们担心会根据疾病的严重程度产生不同的治疗效果,并且他们的经验表明,中度至重度髋骨关节炎的患者对大多数保守治疗的反应并不理想。尽管对数据进行的事后探索性分析显示,与主动治疗和假手术治疗的疾病严重程度亚组相比,疼痛程度(P = .76)和功能改善(P = .38)的改善程度没有显着差异,但这是有可能的。怀特及其同事质疑主动干预的剂量和含量。我们评估了一个旨在匹配澳大利亚和国际上常见临床实践参数的程序。具有更多练习次数和更长监督时间的更密集计划是否更有效,尚待检验。然而,考虑到长期坚持治疗存在问题,因此需要在诸如骨关节炎之类的慢性疾病的情况下考虑该方案的可行性。第三,作者推测,不良事件可能是由于髋关节推力操纵而得以维持的。考虑到该计划的多模式性质,我们无法确定不良事件的原因。然而,在另一项髋骨关节炎的试验中,使用同一技术几乎未发现不良事件。1

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