β-blockers as initial therapy for hypertension

摘要

Beta-Blockers are associated with lower mortality and cardiovascular events than placebo when prescribed for patients with heart failure or acute myocardial infarction.1 However, the benefits of (3-block-ers for initial treatment of hypertension are less clear. This JAMA Clinical Evidence Synopsis summarizes a recently published Coch-rane review of randomized clinical trials (RCTs) regarding associations of (3-blockers with all-cause mortality and cardiovascular events when used as initial therapy for hypertension.2