Open Prospective Study to Evaluate Cardiovascular Risk Factors and Renal Function in 2 Dosage Regimens of Tacrolimus Combined With Mycophenolate Mofetil and Steroids in Renal Transplant Patients: 5-Year Results

摘要

Background. Cyclosporine and tacrolimus (TAC) are the most potent immunosuppressants. TAC is considered less nephrotoxic, but may be an important factor in chronic graft dysfunction. The aim of the study was to evaluate kidney function and cardiovascular risk profile in 2 groups of low immunological risk kidney allograft recipients receiving 2 TAC dosages.