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Ankle-arm blood pressure monitoring does not correlate with serum lipoprotein a in renal transplant recipients.

机译:肾移植受者的踝臂血压监测与血清脂蛋白a不相关。

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OBJECTIVE: Lipoprotein a [Lp(a)] is a strong biochemical risk factor that predicts posttransplant atherosclerosis. In this study we measured the ankle to arm blood pressure index (AAI) as a predictor of clinical atherosclerosis and assessed its relationship to serum Lp(a) values among 60 renal transplant recipients. MATERIALS AND METHODS: After measuring the AAI in a recumbent position, biochemical factors including cholestrol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and Lp(a) were measured by commercial kits in 60 renal transplant and 30 healthy subjects. Results were analyzed using SPSS. RESULTS: Lp(a) concentrations were significantly higher among transplant recipients compared with the control group (P < .05). AAI was similar between the kidney transplant recipients and controls, showing no significant correlation of Lp(a) concentration with AAI. CONCLUSION: Increased serum Lp(a) in renal transplant recipients, a potent biochemical risk factor for atherosclerosis, was not associated with abnormal AAI.
机译:目的:脂蛋白a [Lp(a)]是一种强烈的生化危险因素,可预测移植后的动脉粥样硬化。在这项研究中,我们测量了踝臂血压指数(AAI)作为临床动脉粥样硬化的预测指标,并评估了60例肾移植受者中其与血清Lp(a)值的关系。材料与方法:在横卧位置测量AAI后,通过商业试剂盒对60例肾移植和30例健康受试者的胆固醇,三酸甘油脂,低密度脂蛋白胆固醇,高密度脂蛋白胆固醇和Lp(a)等生化因子进行了测量。使用SPSS分析结果。结果:与对照组相比,移植受者中的Lp(a)浓度显着更高(P <.05)。肾移植受者和对照之间的AAI相似,显示Lp(a)浓度与AAI没有显着相关性。结论:肾移植受者血清Lp(a)升高是动脉粥样硬化的潜在生化危险因素,与AAI异常无关。

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