Aspirin reduces long-term risk of cancer in obese patients

摘要

Obesity is associated with a greater risk of colorectal cancer in patients with Lynch syndrome (LS) - also known as hereditary non-polyposis colon cancer - but this risk is offset by taking aspirin regularly, according to an international study published in the Journal of Clinical Oncology on 17 August 2015. The study confirms other literature that shows obesity is a risk factor for colorectal cancer. "What was surprising was that the effect was much greater in those who also had a genetic predisposition and that the excess was largely cancelled by having taken aspirin for two years," says John Burn, a professor at Newcastle University, who led the research. "This provides an insight into how obesity influences the cancer process."