RNA interference discovery wins US researchers the Nobel Prize for medicine

摘要

Two US scientists have been awarded the Nobel Prize for medicine for their discovery of RNA interference, a mechanism for silencing genes that could lead to the development of new treatments. Andrew Fire of Stanford University School of Medicine and Craig Mello of the University of Massachusetts Medical School published their seminal work in Nature in 1998, which detailed how fragments of RNA can interfere with the expression of a particular disease-causing gene and effectively shut it down.