Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial

Khanna Reena; Bressler Brian; Levesque Barrett G.; Zou Guangyong; Stitt Larry W.; Greenberg Gordon R.; Panaccione Remo; Bitton Alain; Pare Pierre; Vermeire Severine; DHaens Geert; MacIntosh Donald; Sandborn William J.; Donner Allan; Vandervoort Margaret K.; Morris Joan C.; Feagan Brian G.

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Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial

机译：早期联合免疫抑制治疗克罗恩病（REACT）：一项随机对照试验

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Background Conventional management of Crohn's disease features incremental use of therapies. However, early combined immunosuppression (ECI), with a TNF antagonist and antimetabolite might be a more effective strategy. We compared the efficacy of ECI with that of conventional management for treatment of Crohn's disease.

机译：背景技术克罗恩氏病的常规治疗以逐渐使用疗法为特征。然而，早期联合免疫抑制（ECI），TNF拮抗剂和抗代谢药物可能是更有效的策略。我们比较了ECI和常规治疗克罗恩氏病的疗效。

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《The Lancet 》 |2015年第10006期| 共10页
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Khanna Reena; Bressler Brian; Levesque Barrett G.; Zou Guangyong; Stitt Larry W.; Greenberg Gordon R.; Panaccione Remo; Bitton Alain; Pare Pierre; Vermeire Severine; DHaens Geert; MacIntosh Donald; Sandborn William J.; Donner Allan; Vandervoort Margaret K.; Morris Joan C.; Feagan Brian G.;
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1. Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial [J] . Khanna Reena, Bressler Brian, Levesque Barrett G., The Lancet . 2015 ,第10006期

机译：早期联合免疫抑制治疗克罗恩病（REACT）：一项随机对照试验
2. Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED) trial: A multi-centre, double-masked, factorial randomised controlled trial [J] . Rathie Rajendram, Richard WJ Lee, Mike J Potts, Trials . 2008 ,第1期

机译：甲状腺眼疾病联合免疫抑制和放射疗法试验方案（CIRTED）：一项多中心，双掩蔽，因子分解随机对照试验
3. Combined immunosuppression and radiotherapy in thyroid eye disease (CIRTED): a multicentre, 2 x 2 factorial, double-blind, randomised controlled trial [J] . Rajendram Rathie, Taylor Peter N., Wilson Victoria J., The lancet. Diabetes & endocrinology. . 2018 ,第4期

机译：联合免疫抑制和放射治疗甲状腺眼疾病（CIRTED）：多期，2 x 2因子，双盲，随机对照试验
4. Disabling and Reoperation in Patients with Crohn's Disease Subject to Early Surgery or Immunosuppression: A Bayesian Network Prognostic Model [C] . Cláudia Camila Dias, Fernando Magro, Pedro Pereira Rodrigues IEEE International Symposium on Computer-Based Medical Systems . 2016

机译：受早期手术或免疫抑制作用的克罗恩病患者的残疾和再次手术：贝叶斯网络预后模型
5. The early external cephalic version (ECV) trial: A randomised controlled trial of ECV beginning at between 34--36 weeks compared to 37--38 weeks gestation. [D] . Hutton, Eileen Katherine McNally. 2003

机译：早期体外头颅试验（ECV）：一项ECV随机对照试验始于妊娠34--36周，而妊娠37--38周。
6. Protocol for the combined immunosuppression radiotherapy in thyroid eye disease (CIRTED) trial: A multi-centre double-masked factorial randomised controlled trial [O] . Rathie Rajendram, Richard WJ Lee, Mike J Potts, 2008

机译：甲状腺眼疾病联合免疫抑制和放射疗法试验方案（CIRTED）：一项多中心双掩蔽析因性随机对照试验
7. Trial Protocol Communicating DNA-based risk assessments for Crohn's disease: a randomised controlled trial assessing impact upon stopping smoking:Communicating DNA-based risk assessments for Crohn's disease: a randomised controlled trial assessing impact upon stopping smoking [O] . Whitwell, Sophia C L, Mathew, Christopher G, Lewis, Cathryn M, 2011

机译：试验方案对克罗恩病进行基于DNA的风险评估交流：评估对戒烟影响的随机对照试验：对克罗恩病进行基于DNA的风险评估交流：对戒烟影响的随机对照试验

Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial

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