首页> 外文期刊>The Journal of Urology >Long-term device outcomes of artificial urinary sphincter reimplantation following prior explantation for erosion or infection
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Long-term device outcomes of artificial urinary sphincter reimplantation following prior explantation for erosion or infection

机译:事先移植后因侵蚀或感染而进行人工尿道括约肌再植入的长期装置结果

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Purpose We evaluated clinical outcomes in patients treated with artificial urinary sphincter reimplantation after artificial urinary sphincter explantation for erosion or infection. Materials and Methods We identified 704 consecutive artificial urinary sphincter implantation procedures performed at our institution from 1998 to 2012, including 497 (71%) as primary implantation and 138 (20%) as revision surgery for device malfunction. A total of 69 patients (10%) had undergone at least 1 prior artificial urinary sphincter explantation secondary to urethral erosion and/or device infection, of whom 36 (52%) were treated with 2 to 5 prior reimplantation procedures. Patient followup was performed through office examination, or written or telephone correspondence. Results Patients treated with artificial urinary sphincter reimplantation had a median age of 78 years (IQR 72, 80) and a median followup of 34 months (IQR 5, 61). Artificial urinary sphincter reimplantation was done a median of 9 months (IQR 6, 13) after explantation. Patients treated with reimplantation after erosion or infection were more likely to require repeat explantation than those with primary implantation (13 of 69 or 19% vs 32 of 497 or 6.4%, p = 0.002). However, when evaluating repeat procedures, the 5-year device survival rate after reimplantation due to erosion or infection vs primary implantation was 68% vs 76% (p = 0.38). Conclusions Our findings suggest that artificial urinary sphincter reimplantation after explantation for urethral erosion and/or device infection is associated with an increased rate of recurrent erosion/infection requiring repeat explantation. However, in appropriately selected and counseled patients clinically acceptable long-term device use can be achieved.
机译:目的我们评估了在人工尿道括约肌移植后因侵蚀或感染而接受人工尿道括约肌再植治疗的患者的临床结局。材料与方法我们确定了1998年至2012年间在本机构进行的704例人工尿道括约肌植入手术,其中497例(71%)为原位植入术,138例(20%)为设备失灵的翻修手术。共有69例患者(10%)在尿道糜烂和/或器械感染后至少接受了1次人工尿道括约肌的人工植入,其中36例(52%)接受了2至5例的再植入手术。通过办公室检查或书面或电话通信对患者进行随访。结果人工尿道括约肌再植治疗的患者中位年龄为78岁(IQR 72,80),中位随访时间为34个月(IQR 5,61)。人工尿道括约肌再植在中位后9个月(IQR 6,13)进行。侵蚀或感染后接受再植入治疗的患者比初次植入的患者更有可能需要再次植入(69例中的13例或19%,497例中的32例或6.4%,p = 0.002)。但是,在评估重复手术时,由于侵蚀或感染而进行的再植入与原发植入相比,其5年器械存活率分别为68%和76%(p = 0.38)。结论我们的研究结果表明,由于尿道糜烂和/或装置感染而在移植后人工尿道括约肌再植入与复发性糜烂/感染率的增加相关,需要再次植入。然而,在适当地选择和劝告患者可以实现临床上可接受的长期装置一起使用。

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