Sarcoidosis of the Prostate

摘要

A 65-year-old African-American man presented with 7.2 ng/mL prostate specific antigen (PSA). A trans-rectal ultrasound guided 12-core biopsy of the prostate was performed.Microscopically, core biopsy sections revealed noncaseating granulomas localized to the left side of the gland without evidence of prostate cancer. Special stains for acid-fast bacilli and fungi were negative. Two years earlier the patient had been diagnosed and treated for pulmonary sarcoidosis. He denied a history of urinary tract infection, intraves-ical bacillus Calmette-Guerin (BCG) therapy, prior prostate biopsy or transurethral resection of the prostate. The histological appearance suggested prostatic sarcoidosis and was consistent with the clinical history. This case is an example of systemic sarcoidosis with prostatic involvement.