Unusual presentation of urothelial carcinoma of the bladder with noncontiguous rectal and diffuse muscular skeletal metastases.

摘要

BAn 83-year-old man presented with frequent bowel movements and weight loss in the last 6 months. History was remarkable for hypertension and diabetes mellitus. Digital rectal examination revealed a tumor 3 cm from the anal verge, which was subsequently confirmed by rectoscopy. Biopsy revealed poorly differentiated carcinoma. The tumor cells stained strongly positive for CK7, weakly positive for CK20, and negative for CDX-2 and S-100. Therefore, primary adeno-carcinoma of the colon was less likely and tumor growth of urothelial origin was suspected.