Regioselective Synthesis of Highly Substituted Imidazoles via the Sequential Reaction of Allenyl Sulfonamides and Amines

摘要

A novel synthesis of imidazoles from electron-withdrawing group-substituted allenyl sulfonamides with amines was developed. The 4- and 5-functionalized imidazoles were constructed regioselectively, which depended on the substituents on the nitrogen atoms.