Palladium-Catalyzed Alkynylation of Morita-Baylis-Hillman Carbonates with (Triisopropylsilyl)acetylene on Water

摘要

Direct alkynylation of Morita-Baylis-Hillman carbonates with (triisopropylsilyl)acetylene catalyzed by a Pd(OAc)(2)-NHC complex was developed "on water" to give the corresponding 1,4-enynes. The significant effects of water amount in the solvent on further transformations of 1,4-enynes were investigated.