Regioselective Ortho Olefination of Aryl Sulfonamide via Rhodium- Catalyzed Direct C?H Bond Activation

摘要

Rh(III)-catalyzed ortho C?H olefination of aryl sulfonamide directed by the SO_2NHAc group is reported. This oxidative coupling process is achieved highly efficiently and selectively with a broad substrate scope. The reactions of Ntosylacetamide with acrylate esters afford ortho-alkenylated benzofused five-membered cyclic sulfonamides, whereas styrenes provide the direct diolefination products.