A Co(II)-catalyzed aerobic intramolecular C-O bond formation via selective (sp(3))C-H bond activation: facile access to dihydro-benzoxazinone derivatives

摘要

We have developed an efficient Co(II)-catalyzed intramolecular C-O bond formation via cross dehydrogenative coupling (CDC) of acids with (sp(3))C-H bond by using oxygen as the terminal oxidant. This strategy allows convenient access to a series of ring fused dihydro-benzoxazinones and its derivatives. (C) 2014 Elsevier Ltd. All rights reserved.