首页> 外文期刊>Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry >'Green' synthesis of 1,4-disubstituted 5-iodo-1,2,3-triazoles under neat conditions, and an efficient approach of construction of 1,4,5-trisubstituted 1,2,3-triazoles in one pot
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'Green' synthesis of 1,4-disubstituted 5-iodo-1,2,3-triazoles under neat conditions, and an efficient approach of construction of 1,4,5-trisubstituted 1,2,3-triazoles in one pot

机译:在纯净条件下“绿色”合成1,4-二取代的5-碘-1,2,3-三唑,以及在一个锅中构建1,4,5-三取代的1,2,3-三唑的有效方法

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摘要

An environmentally friendly and efficient method for synthesis of 1,4-disubstituted 5-iodo-1,2,3-triazoles through [Cu(phen)(PPh3)(2)]NO3-catalyzed cycloaddition of organic azides and iodoalkynes under solvent-free conditions was developed. Based on this, a one-pot method for the synthesis of fully substituted 1,2,3-triazoles via cycloaddition/Suzuki reactions was also demonstrated in this report. (C) 2014 Elsevier Ltd. All rights reserved.
机译:一种在环境友好的条件下通过[Cu(phen)(PPh3)(2)] NO3催化的有机叠氮化物和碘代炔烃环加成反应合成1,4-二取代的5-碘-1,2,3-三唑的环保,高效方法。自由条件得以发展。在此基础上,本报告还证明了一锅法通过环加成/铃木反应合成完全取代的1,2,3-三唑。 (C)2014 Elsevier Ltd.保留所有权利。

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