Synthesis of hexahydro[2]benzopyrano[3,4-c]pyrroles as serotonin 5-HT_(2C) receptor agonists via intramolecular hetero Diels-Alder reactions

Takao Kiyoi; Mark Reid; Stuart Francis

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Synthesis of hexahydro[2]benzopyrano[3,4-c]pyrroles as serotonin 5-HT_(2C) receptor agonists via intramolecular hetero Diels-Alder reactions

机译：分子内杂Diels-Alder反应合成5-羟色胺5-HT_（2C）受体激动剂六氢[2]苯并吡喃并[3,4-c]吡咯

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[2]Benzopyrano[3,4-c]pyrroles were synthesized via an intramolecular hetero Diels-Alder reaction. The reaction was applicable to a wide range of substrates and the products could be easily converted into serotonin 5-HT2c receptor agonists.

机译：通过分子内杂Diels-Alder反应合成了[2]苯并吡喃并[3,4-c]吡咯。该反应适用于广泛的底物，并且产物可以容易地转化为5-羟色胺5-HT 2c受体激动剂。

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |2011年第27期|共4页
作者
Takao Kiyoi; Mark Reid; Stuart Francis;
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Intramolecular hetero Diels-Alder reaction; 2Benzopyrano3; 4-cpyrroles; Serotonin 5-HT_(2C) receptor agonists; Microwave-assisted synthesis;

机译：分子内异狄尔斯-阿尔德反应;[2]苯并吡喃并[3;4-c]吡咯;5-羟色胺5-HT_（2C）受体激动剂;微波辅助合成;

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1. Synthesis of hexahydro[2]benzopyrano[3,4-c]pyrroles as serotonin 5-HT_(2C) receptor agonists via intramolecular hetero Diels-Alder reactions [J] . Takao Kiyoi, Mark Reid, Stuart Francis Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2011,第27期

机译：分子内杂Diels-Alder反应合成5-羟色胺5-HT_（2C）受体激动剂六氢[2]苯并吡喃并[3,4-c]吡咯
2. Synthesis of hexahydro[2]benzopyrano[4,3-c]pyridines as serotonin 5-HT_(2C) receptor agonists via intramolecular hetero Diels-Alder reactions [J] . Yasuko Kiyoi, Steven Laats, Takao Kiyoi Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2011,第27期

机译：分子内杂Diels-Alder反应合成5-羟色胺5-HT_（2C）受体激动剂六氢[2]苯并吡喃并[4,3-c]吡啶
3. Stereoselective synthesis of tetrahydro-2H-[2]benzopyrano[3,4-c]pyrrol-3-ones and related compounds as precursors of serotonin 5-HT_(2C) receptor agonists [J] . Stuart Francis, Takao Kiyoi, Mark Reid Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2011,第27期

机译：立体选择性合成四氢-2H- [2]苯并吡喃并[3,4-c]吡咯-3-酮和相关化合物作为5-羟色胺5-HT_（2C）受体激动剂的前体
4. Synthesis of Nitrogen Heterocycles by Hetero Diels-Alder Reactions [C] . Rodolfo Nesi, Donatella Giomi, Stefania Turchi Edition of the A. Corbella" summer school on organic synthesis" . 1999

机译：杂Diels-Alder反应合成氮杂环
5. I. Studies toward the formal synthesis of (+)-aldosterone. II. Type 2 intramolecular hetero Diels-Alder reaction and the discovery of a novel tandem hetero Diels-Alder reaction. [D] . Bear, Brian Richard. 2001

机译：I.对（+）-醛固酮的形式合成的研究。二。 2型分子内杂Diels-Alder反应和新型串联杂Diels-Alder反应的发现。
6. Synthesis of 25-Disubstituted Octahydroquinolin-4-ones via an Intramolecular Hetero Diels-Alder Reaction [O] . Juan M. Ruiz, María M. Afonso, J. Antonio Palenzuela 2007

机译：分子内杂Diels-Alder反应合成25-二取代的八氢喹啉-4-酮
7. Theoretical Study of Intramolecular 4 + 2 Cycloadditions of Iminoacetonitriles: A New Class of Azadienophiles for Hetero Diels-Alder Reactions [O] . -1

机译：亚氨基乙腈的分子内4 + 2环加入的理论研究：杂菌Diels反应的新类Azienophiles

Synthesis of hexahydro[2]benzopyrano[3,4-c]pyrroles as serotonin 5-HT_(2C) receptor agonists via intramolecular hetero Diels-Alder reactions

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