Selective functionalization of p-cyclodextrin:efficient conversions of 2,3-alloepoxypyranosides to 2,3-mannoepithiopyranosides

摘要

A two-step one-pot method was established to efficiently convert up to three 2,3-alloepoxypyranoside residues to the 2,3-mannoepithiopyranosides within the P-cyclodextrin belts.Many artificial enzymes have been made by the func-tionalizations of cyclodextrins(CDs)whose cavities afford substrate-binding sites.Mono-to poly-function-alizations including homo and hetero ones on the primary hydroxyl sides have been extensively studied.