Phosphinite-and phosphite-based type I palladacycles as highly active catalysts for addition reactions of arylboronic acids with aldehydes,alpha,beta-unsaturated ketones,alpha-ketoesters,and aldimines

摘要

Phosphinite-and phosphite-based type I palladacycle-catalyzed additions of arylboronic acids with aldehydes,alpha,beta-unsat-urated ketones,alpha-ketoesters,and aldimines are described.Our study showed that readily available phosphinite-and phosphite-based type I palladacycles could possess higher catalytic activity than phosphine-based palladacycles and were highly active,practical catalysts.Our study may pave the road for development of optically active phosphinite-and phosphite-based palladacycles for asymmetric catalysis.