Hydrosilylation of alkynes catalyzed by ruthenium carbene complexes

摘要

Hydrosilylation of terminal alkynes with a variety of silanes catalyzed by Cl_2(PCy_3)_2Ru=CHPh(1)affords mainly the Z-isomer via trans addition in excellent yields.The presence of a hydroxyl group in close proximity to the triple bond was observed to exert a strong directing effect,resulting in the highly selective formation of the alpha-isomer.Intramolecular hydrosilylation of a homo-propargylic silyl ether was demonstrated to give the cis addition product.The significant growth in olefin metathesis chemistry can primarily be attributed to the development of new and effective metathesis catalysts.In particular,Grubbs' ruthenium complexes,Cl_2(PCy_3)_2Ru=CHPh(l)_2N and Cl_2(PCy_3)(NHC)Ru=CHPh(2),have demonstrated remarkable reactivity in the presence of a variety of functional groups.