Synthesis of 2-(ethylsulfanyl)aniline derivatives through the unexpected ring opening of N-substituted-2(3H)-benzothiazolones

摘要

The decarbalkoxylations of disubstituted geminal diesters by water-DMSO with added salts(KCN or NaCN)is a convenient preparative route leading to the corresponding monoesters.Herein,we described an efficient and very simple methodology for the preparation of 2-(ethylsulfanyl)aniline derivatives through the unexpected ring opening of the corresponding N-substituted-2(3H)-benzothiazolones in the presence of disubstituted geminal diester,KCN,and water-DMSO.