Enantioselective total synthesis of polyoxygenated cyclohexanoids:(+)-streptol,ent-RKTS-33 and putative '(+)-parasitenone'.Identity of parasitenone with (+)-epoxydon

摘要

Short,simple and enantioselective syntheses of the natural product (+)-streptol,the non-peptide apoptosis inhibitor ent-RKTS-33 and the putative structure of 'parasitenone' have been accomplished from the readily available chiral building block.'Parasitenone' has been shown to be identical with the known natural product epoxydon.