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Highly diastereoselective synthesis of tetrahydrobenzofuran derivatives by palladium-catalyzed reaction of propargylic esters with substituted beta-dicarbonyl compounds

机译:钯催化的炔丙基酯与取代的β-二羰基化合物的非对映选择性合成四氢苯并呋喃衍生物

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摘要

Reactions of propaigylic esters with 2-substituted cyclohexane-1,3-diones and 2-oxocyclohexanecarboxylic esters in the presence of palladium catalyst are described Substituted tetrahydrobenzofuran derivatives having a quaternary carbon stereocenter were synthesized in a highly diastereoselective manner (C) 2010 Elsevier Ltd All rights reserved
机译:描述了在钯催化剂的存在下丙酸酯与2-取代的环己烷-1,3-二酮和2-氧代环己烷羧酸酯的反应以高度非对映选择性的方式合成了具有季碳立体中心的取代的四氢苯并呋喃衍生物(C)2010 Elsevier Ltd All保留权利

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