Convenient and efficient method for synthesis of 2,4,6-triarylpyridines using catalytic amount of PEG(1000)-based dicationic acidic ionic liquid under solvent-free conditions

摘要

A convenient and efficient method for synthesis of substituted 2,4,6-triarylpyridines by the reaction of chalcones and ammonium acetate or via one-pot, three-component condensation of aromatic aldehydes with acetophenones and ammonium acetate has been developed by using the efficient catalyst PEG(1000)-based dicationic acidic ionic liquid (PEG(1000)-DAIL) under solvent-free conditions. Recycling studies have shown that the PEG(1000)-DAIL can be readily recovered and reused several times without significant loss of activity.