Triacetonide of Glucoheptonic Acid in the Scalable Syntheses of D-Gulose, 6-Deoxy-D-gulose, L-Glucose, 6-Deoxy-L-glucose, and Related Sugars

摘要

Ease of separation of petrol-soluble acetonides derived from the triacetonide of methyl glucoheptonate allows scalable syntheses of rare sugars containing the L-gluco or D-gulo structural motif with any oxidation level at the C6 or Cl position of the hexose, usually without chromatography: meso-D-glycero-D-guloheptitol available in two steps is an ideal entry point for the study of the biotechnological production of heptoses.