Expanding the Forefront of Strong Organic Bronsted Acids: Proton-Catalyzed Hydroamination of Unactivated Alkenes and Activation of Au(I) for Alkyne Hydroamination

摘要

The synthesis of a solid, bench-stable, strong organic Bronsted acid with a computed pK(a) of 0.9 is reported. An X-ray crystal structure and DFT calculations are provided which offer insight into the bonding of this acid. The application of this strong organic Bronsted acid as a catalyst for the intermolecular hydroamination of unactivated alkenes and as an activator for Au(I)-catalyzed alkyne hydroamination with anilines is described.