Rhodium-catalyzed three-component reaction between silylacetylene and two ketenes leading to 1,3-enynes bearing a carboxylic ester group via double insertion of ketenes

摘要

The first cross-reaction between a terminal silylacetylene and two ketene molecules leading to 1,3-enynes bearing a carboxylic ester group via double insertion of ketenes is achieved using a cationic rhodium complex catalyst. This reaction is applicable for various symmetrical and unsymmetrical ketenes with good stereoselectivities.