首页> 外文期刊>Optics Communications: A Journal Devoted to the Rapid Publication of Short Contributions in the Field of Optics and Interaction of Light with Matter >An ultrasensitive optical label-free polymeric biosensor based on concentric triple microring resonators with a central microdisk resonator
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An ultrasensitive optical label-free polymeric biosensor based on concentric triple microring resonators with a central microdisk resonator

机译:基于同心三重微环谐振器和中央微盘谐振器的超灵敏光学无标签聚合物生物传感器

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In this paper we propose an optical label-free biosensor based on a polymeric platform. Label-free biosensors have not the drawbacks and stability problems of commercialized devices which are used for detection of labeled molecules. In addition, we choose polymeric platform, due to simple and low cost fabrication process and also high biocompatibility properties. The suggested structure consists of concentric triple ring resonators along with a disk resonator which offers deeper notches, higher sensitivity and vaster detection area with respect to other similar configurations such as single ring resonator, double concentric ring resonators, etc. Our numerical simulations based on the finite difference time domain (FDTD) method, show that in optimized structure, a transmission notch depth of 48.7 dB for sensor at rest and a free spectral range of 56 nm are achievable. In addition, resonance wavelength sensitivity and output power sensitivity of sensor are 1000 nm/RIU and 1.8 x 10(4) dB/RIU, respectively. The external radius of outer ring resonator is only 5 mu m, and detection area of the sensor is 40.37 mu m(2). With this small size, to the best of our knowledge, the obtained notch depth and sensitivity parameters are one of the highest values in ring resonator-based biosensors reported to date. (C) 2015 Elsevier B.V. All rights reserved.
机译:在本文中,我们提出了一种基于聚合物平台的无光学标签的生物传感器。无标记生物传感器不具有用于检测标记分子的商业化设备的缺点和稳定性问题。此外,由于简单,低成本的制造过程以及高生物相容性,我们选择聚合物平台。建议的结构由同心三环谐振器和一个盘式谐振器组成,相对于其他类似配置(例如单环谐振器,双同心环谐振器等),圆盘谐振器可提供更深的切口,更高的灵敏度和更大的检测面积。有限差分时域(FDTD)方法表明,在优化的结构中,静止传感器的传输陷波深度为48.7 dB,自由光谱范围为56 nm。此外,传感器的共振波长灵敏度和输出功率灵敏度分别为1000 nm / RIU和1.8 x 10(4)dB / RIU。外环谐振器的外半径仅为5μm,传感器的检测面积为40.37μm(2)。据我们所知,这种小尺寸的传感器所获得的陷波深度和灵敏度参数是迄今为止报道的基于环形谐振器的生物传感器的最高值之​​一。 (C)2015 Elsevier B.V.保留所有权利。

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