Ventilator waveforms-based patient-ventilator asynchrony detection: valuable tool or a pipe dream in the clinical setting?

摘要

Mechanical ventilation (MV) is a consolidated lifesaving procedure for patients with respiratory failure. Assuming that respiratory failure depends on an imbalance between the force-generating capacity of the inspiratory muscles available and the actual inspiratory mechanical workload that opposes the generation of air flow and tidal volume (1), the role of MV is to restore that imbalance and warrant adequate alveolar ventilation (Fig. 1, left). The equation of motion of the respiratory system is very powerful in describing how MV interacts with patients. During controlled MV (Eq. 2, Fig. 1), the only pump working is the ventilator that must generate enough elastic, resistive, and threshold pressure to deliver a target tidal volume through the generation of inspiratory flow.