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首页> 外文期刊>Critical care : >Knowing who would respond to a recruitment maneuver before actually doing it--this might be a way to go.
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Knowing who would respond to a recruitment maneuver before actually doing it--this might be a way to go.

机译:在实际执行招募策略之前,先知道谁会做出反应,这可能是一条路。

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Using recruitment manoeuvres in acute lung injury remains a controversial issue because no convincing outcome data support their general use, although many physiological studies have demonstrated beneficial effects on lung compliance, end-expiratory lung volume and gas exchange. One of the reasons why physiologically meaningful observations do not translate into clear clinical benefit could be the heterogeneity of the studied patient population. In patients with consolidated lungs and only limited potential for recruitment, manoeuvres might be harmful, whereas in patients with high potential for recruitment they might be helpful. However, when those populations are mixed any signal may be lost because of counteracting effects, depending on how the patient population was mixed. We do not currently have any simple tool that may readily be applied at the bedside to assess the recruitment potential in an individual patient, which would be a sine qua non for identifying a homogeneous population in a recruitment study. Therefore, the method presented by Jacob Koefeld-Nielsen and colleagues in the previous issue of Critical Care provides us with a simple method that could be used at the bedside to assess recruitment potential before the manoeuvre is applied.
机译:在急性肺损伤中使用募集演习仍然是一个有争议的问题,因为没有令人信服的结果数据支持其普遍使用,尽管许多生理研究已证明对肺顺应性,呼气末肺体积和气体交换有有益作用。生理上有意义的观察结果不能转化为明确的临床益处的原因之一可能是所研究患者人群的异质性。在肺部巩固且仅具有有限的募集潜力的患者中,演习可能是有害的,而在具有较高募集潜力的患者中,它们可能会有所帮助。但是,当这些人群混合在一起时,由于抵消效果,可能会丢失任何信号,具体取决于患者人群的混合方式。我们目前没有任何简单的工具可以轻易地在床边应用来评估单个患者的募集潜力,这是在募集研究中识别同质人群的必要条件。因此,Jacob Koefeld-Nielsen及其同事在上一期《重症监护》中提出的方法为我们提供了一种简单的方法,可以在床旁使用该方法来评估应用该操作之前的招募潜力。

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